Doctor Life

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Autophagy Revital

Urolithin A and spermidine

152,99 zł

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Build your routine

Four categories. Find the support that fits your needs.

  • Focused support for healthy cellular aging
  • Complements a daily routine focused on longevity
  • Urolithin A, studied for mitochondrial health

Overview

A considered approach to longevity beyond a conventional vitamin supplement. Autophagy Revital combines three carefully selected ingredients associated with research on cellular renewal, mitochondria, and healthy aging.

At the heart of the formula / Autophagy Revital

Thoughtful support. Clear purpose.

  1. 01Focused support for healthy cellular aging
  2. 02Complements a daily routine focused on longevity
  3. 03Urolithin A, studied for mitochondrial health
  4. 04Spermidine from natural buckwheat sprout extract
  5. 05Three complementary ingredients in one capsule
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Autophagy Revital

Made for your daily routine.

Urolithin A sits at the center of the formula. Gut microbes can produce this metabolite from compounds found in foods such as pomegranates, but the amount varies between individuals. Spermidine from buckwheat sprouts and standardized long pepper extract containing piperlongumine complete the blend.

The three-ingredient formula comes in one plant-based capsule daily. It is designed for adult women and men interested in cellular and mitochondrial function as part of a long-term wellness routine.

Doctor Life / 02

Autophagy Revital

Why does cellular renewal matter?

Cells constantly use energy, build new structures, and remove components that no longer work properly. Autophagy is one of their natural cleanup processes; mitophagy specifically concerns mitochondria. These quality-control processes help cells maintain balance and use energy efficiently. Their activity can change with age, making them an important area of healthy-aging research.

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Autophagy Revital

What research informs Autophagy Revital?

Urolithin A has been studied in relation to mitophagy, the natural process of recycling mitochondria. Adult trials have reported changes in mitochondrial biomarkers, and studies in middle-aged and older adults have found improvements in some measures of muscle strength or endurance. These ingredient studies informed its place at the center of the formula. Their results do not establish equivalent effects for Autophagy Revital.

Ingredients / Doctor Life

Every ingredient. Clearly explained.

Each ingredient, its form and quantity — in one place.

Serving1 capsule
Ingredient amounts for the servings shown in the table.
Ingredient1 capsule
Long pepper extract12 mg
of which piperlongumine10 mg
Urolithin A from pomegranate100 mg
Buckwheat sprout extract150 mg
including spermidine0.5 mg

*NRV: Nutrient Reference Value

Full ingredient list

Buckwheat sprout extract (Fagopyrum esculentum Moench), including spermidine; urolithin A from pomegranate fruit (Punica granatum); long pepper fruit extract (Piper longum L.), including piperlongumine; capsule shell: pullulan.

How to use

Part of your daily rhythm.

01

How to use

Adults: Take 1 capsule daily with food.

02

Important information

Do not exceed the recommended daily serving. Food supplements should not replace a varied diet. Maintain a balanced diet and a healthy lifestyle. Do not use in children or during pregnancy or breastfeeding. Store at room temperature, up to 25°C, out of reach of young children.

Science & sources

Understand the formula.

The strongest evidence concerns urolithin A, which has been studied in adults in relation to mitochondrial health, muscle endurance, and physical performance.

These publications concern the studied ingredients or formulas. They do not all evaluate the finished Doctor Life product, and research results do not guarantee individual outcomes.

01The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

Pénélope A. Andreux, William Blanco-Bose, Dongryeol Ryu, Frédéric Burdet, Mark Ibberson, Patrick Aebischer, Johan Auwerx, Anurag Singh, Chris Rinsch

Nature Metabolism (2019), 1(6), 595-603. DOI: 10.1038/s42255-019-0073-4; PMID: 32694802.

The first human study demonstrated that orally administered urolithin A was bioavailable and produced favorable changes in markers associated with mitochondrial and cellular health. The publication opened the way for further human research.

Read publication ↗
02Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults

Anurag Singh, Davide D’Amico, Pénélope A. Andreux, Andréane M. Fouassier, William Blanco-Bose, Mal Evans, Patrick Aebischer, Johan Auwerx, Chris Rinsch

Cell Reports Medicine (2022), 3(5), 100633. DOI: 10.1016/j.xcrm.2022.100633; PMID: 35584623.

In a randomized trial in middle-aged adults, urolithin A was associated with improved muscle strength and favorable changes in selected performance measures and markers of mitochondrial health. The findings contribute to research on mitochondrial renewal and physical function.

Read publication ↗
03Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial

Sophia Liu, Davide D’Amico, Eric Shankland, Saakshi Bhayana, Jose M. Garcia, Patrick Aebischer, Chris Rinsch, Anurag Singh, David J. Marcinek

JAMA Network Open (2022), 5(1), e2144279. DOI: 10.1001/jamanetworkopen.2021.44279; PMID: 35050355.

Four months of supplementation in older adults improved endurance in the muscle groups tested and affected markers associated with mitochondrial health. The findings contribute to research on maintaining physical function with age.

Read publication ↗

FAQ / Autophagy Revital

Good questions. Clear answers.

Talk to us ↗
What is autophagy?

Autophagy is a natural cellular cleanup process that breaks down and reuses worn or unnecessary components. It forms part of the cell's quality-control system and cannot be reliably assessed at home without specialized testing.

How does autophagy differ from mitophagy?

Autophagy is the broader process of removing and recycling cellular components. Mitophagy specifically concerns mitochondria, the structures involved in energy production. Urolithin A is being studied in relation to mitophagy and mitochondrial function.

Why provide urolithin A directly?

Gut microbes can convert ellagitannins from foods such as pomegranates into urolithin A, but this ability varies with the microbiome. Providing urolithin A directly delivers a defined amount of the ingredient.

What does spermidine contribute?

Spermidine is a natural polyamine found in foods and in the body. Researchers study it in cellular processes related to aging and autophagy. In this formula, it comes from standardized buckwheat sprout extract.

How do I take Autophagy Revital?

Adults: take one capsule daily with food. Do not increase the serving. Each bottle provides 60 days of use at the recommended amount.

Is it suitable for vegans?

Yes. The capsule shell is made from pullulan, and the product is labeled vegan and gluten-free. It contains no gelatin.

Can I combine it with medication?

If you take medication, have a diagnosed condition, or are under medical care, consult your doctor or pharmacist before starting. This is particularly relevant to formulas containing several active botanical extracts.