Doctor Life Homocysteine Modulator — 90 plant-based capsules

Pack size: 90 plant-based capsules
Serving: 1 capsule
Servings per pack: 90

ShopVitamins and minerals

Doctor Life

Homocysteine Modulator

Active B vitamins and betaine

64,99 zł

Supports normal homocysteine metabolism
Helps reduce tiredness and fatigue
Supports normal nervous system function

Overview

Four complementary nutrients for methylation and normal homocysteine metabolism. Homocysteine Modulator combines folate, vitamins B6 and B12, and betaine, which participate in connected metabolic pathways.

At the heart of the formula / Homocysteine Modulator

Thoughtful support. Clear purpose.

01Supports normal homocysteine metabolism
02Helps reduce tiredness and fatigue
03Supports normal nervous system function
04Supports normal psychological function
05Four complementary ingredients in one capsule

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Homocysteine Modulator

Made for your daily routine.

The formula uses active vitamin forms: Quatrefolic® methylfolate, methylcobalamin, and pyridoxal-5-phosphate. These participate in vitamin-dependent metabolic processes. Betaine complements them as a methyl donor involved in an alternative homocysteine pathway.

One capsule daily provides nutrients that support normal homocysteine metabolism, energy metabolism, nervous system function, and psychological function. The focused vegan formula brings them together in one routine.

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Homocysteine Modulator

Why does normal homocysteine metabolism matter?

Homocysteine is an amino acid naturally formed during methionine metabolism. The body converts it into other compounds using nutrients including folate and vitamins B6 and B12. Betaine contributes through another methyl-donation pathway. These processes are part of normal cellular metabolism, informing the combination of nutrients in this formula.

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Homocysteine Modulator

What research informs Homocysteine Modulator?

Clinical studies show that B6, B12, and folate participate in homocysteine metabolism and that supplementation can lower homocysteine levels. Some trials in older adults with mild cognitive impairment and higher homocysteine assessed brain changes and cognitive measures. Studies of 5-MTHF have also examined homocysteine responses in people with MTHFR variants. Betaine works through a different metabolic pathway. These findings inform the ingredient combination but do not establish that the product prevents cognitive decline or cardiovascular disease.

Ingredients / Doctor Life

Every ingredient. Clearly explained.

Each ingredient, its form and quantity — in one place.

Serving1 capsule

Ingredient amounts for the servings shown in the table.
Ingredient	1 capsule
Vitamin B6	10 mg (716%*)
Quatrefolic® folate	400 µg (200%*)
Vitamin B12	100 µg (4000%*)
Betaine (TMG)	500 mg

*NRV: Nutrient Reference Value

Full ingredient list

Beetroot extract (Beta vulgaris L.), including betaine (trimethylglycine, TMG), vitamin B6 (pyridoxal-5-phosphate), vitamin B12 (methylcobalamin), Quatrefolic® folate (glucosamine salt of (6S)-5-methyltetrahydrofolic acid), capsule shell (pullulan).

How to use

Part of your daily rhythm.

How to use

Take 1 capsule daily with food.

Important information

Do not exceed the recommended daily serving. Food supplements should not replace a varied diet. A balanced diet and a healthy lifestyle are recommended. Suitable for vegans and vegetarians. Store at room temperature, up to 25°C, out of reach of young children.

Science & sources

Understand the formula.

These selected publications explore folates, vitamins B6 and B12, and betaine in relation to homocysteine metabolism, cognitive function, and methylation.

These publications concern the studied ingredients or formulas. They do not all evaluate the finished Doctor Life product, and research results do not guarantee individual outcomes.

01Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial

A.D. Smith, S.M. Smith, C.A. de Jager, P. Whitbread, C. Johnston et al.

PLOS ONE (2010), 5(9), e12244. DOI: 10.1371/journal.pone.0012244; PMID: 20838622.

In the two-year VITACOG trial, a combination of vitamins B6 and B12 and folic acid lowered homocysteine levels and was associated with a slower rate of brain atrophy in older adults with mild cognitive impairment. The largest difference was observed in participants with higher homocysteine levels at the start.

Read publication ↗

02Homocysteine lowering by folate-rich diet or pharmacological supplementations in subjects with moderate hyperhomocysteinemia

B. Zappacosta, S. Mastroiacovo, P. Persichilli, M. Pounis, G. Ruggeri et al.

Nutrients (2013), 5(5), 1531–1543. DOI: 10.3390/nu5051531; PMID: 23698160.

In a 13-week study, 5-MTHF significantly lowered homocysteine in people with moderately elevated levels. This active folate form produced an effect comparable to folic acid and a diet enriched with naturally occurring folates.

Read publication ↗

03Effect of folic acid and betaine supplementation on flow-mediated dilation: a randomized, controlled study in healthy volunteers

M. Olthof, T. van Vliet, E. Boelsma, W. Verhoef, H. Zock, M. Katan

Archives of Internal Medicine (2006), 166(17), 1836–1842. DOI: 10.1001/archinte.166.17.1836; PMID: 16871332.

In a controlled study, both folate and betaine substantially lowered homocysteine compared with placebo. The finding illustrates their involvement in complementary pathways of homocysteine metabolism.

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04Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial

C.A. de Jager, A. Oulhaj, R. Jacoby, H. Refsum, A.D. Smith

International Journal of Geriatric Psychiatry (2012), 27(6), 592–600. DOI: 10.1002/gps.2758; PMID: 21780182.

Two years of B-vitamin supplementation lowered homocysteine by approximately 30%. Participants with higher initial levels showed more favorable results for executive function, memory, and overall cognitive performance.

Read publication ↗

FAQ / Homocysteine Modulator

Good questions. Clear answers.

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Who is Homocysteine Modulator for?

The product is intended for adult women and men seeking nutrients that support normal homocysteine metabolism and who prefer active B vitamin forms. It may be considered after discussing homocysteine results and supplement needs with a health professional.

How does active folate differ from folic acid?

The formula uses 5-MTHF, a reduced form of folate used directly in metabolic processes, supplied as the branded ingredient Quatrefolic®.

Why combine folate and betaine?

Folate and betaine contribute to different pathways for converting homocysteine. Vitamins B6 and B12 complement these processes and also support normal nervous system function and energy metabolism.

Should I have homocysteine tested before starting?

Testing is not a requirement for using the supplement, but it can help establish a baseline when clinically appropriate. Discuss results with your doctor, especially if homocysteine is elevated, you have a medical condition, take medication, or have abnormal B12 or folate results.

How many days does a bottle provide?

Each bottle contains 90 capsules. At one capsule daily, it provides a 90-day supply—about three months.

Is it suitable for vegans?

Yes. The formula is suitable for vegans and vegetarians and uses a plant-based pullulan capsule. Take one capsule daily as directed.

Can I take it with medication or other B vitamins?

If you take medication or another B vitamin complex, review the combination with your doctor or pharmacist. They can assess total B6, B12, and folate intake and help avoid unnecessary duplication.

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