Pack size: 60 capsules

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Spermidine®

Spermidine from wheat germ

91,99 zł

A targeted formula for healthy aging
A precisely measured addition of spermidine to your diet
From a natural source rich in polyamines

Overview

A focused formula for a thoughtful approach to healthy aging. Spermidine® Extra Strength 6 mg centers on a naturally occurring polyamine found in our cells and food. It is neither a vitamin nor a stimulant. Spermidine participates in the basic processes that maintain cellular balance. Its connection to autophagy, the cell's system for clearing and recycling worn components, is a key reason for scientific interest.

At the heart of the formula / Spermidine®

Thoughtful support. Clear purpose.

01A targeted formula for healthy aging
02A precisely measured addition of spermidine to your diet
03From a natural source rich in polyamines
04One active ingredient, without a complex blend
05A serving that matches an amount assessed in a clinical study

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Spermidine®

Made for your daily routine.

Wheat germ is a naturally rich dietary source of spermidine. The concentrate provides a clearly stated 6 mg per serving. Earlier wheat germ extract trials often used approximately 0.9–1.2 mg daily; a clinical pilot study published in 2026 used 6 mg daily in older adults.

This focused formula combines a natural source with a stated amount that can be compared with human research. It does not promise rejuvenation or a guaranteed anti-aging effect.

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Spermidine®

Why is spermidine of interest?

Spermidine is a polyamine naturally present in living cells. Polyamines participate in cell growth, protein synthesis, and cellular balance. Research has focused on spermidine’s relationship with autophagy, the process through which cells break down and recycle components. Some cellular spermidine levels change with age. No NRV has been established, and clinical evidence for supplementation is still developing.

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Spermidine®

What does research say about Spermidine®?

Mechanistic research links spermidine with autophagy and cellular maintenance. Human evidence is newer and mixed. In a 2026 pilot trial, 6 mg daily for 13 weeks was well tolerated in adults over 65, with changes in immune and autophagy-related markers in a subgroup. In contrast, a 2022 trial using 0.9 mg daily for 12 months did not improve its primary memory outcome. These findings do not establish an anti-aging benefit or guarantee a specific effect.

Ingredients / Doctor Life

Every ingredient. Clearly explained.

Each ingredient, its form and quantity — in one place.

Ingredient amounts for the servings shown in the table.
Ingredient	1 capsule
Wheat germ concentrate	600 mg
including spermidine	6 mg

*NRV: Nutrient Reference Value

Full ingredient list

Wheat germ concentrate containing spermidine, capsule shell (bulking agent: pullulan).

How to use

Part of your daily rhythm.

How to use

Adults: take 1 capsule daily with food.

Important information

Do not exceed the recommended daily serving. Food supplements should not replace a varied diet. A balanced diet and a healthy lifestyle are recommended. Store at room temperature, away from sunlight and out of reach of young children.

Science & sources

Understand the formula.

Spermidine is a natural polyamine found in cells and food. Its role in the biology of aging is actively studied, including autophagy, cellular balance, immune function, and brain health. Human research is still developing, with recent studies also examining a daily intake of 6 mg.

These publications concern the studied ingredients or formulas. They do not all evaluate the finished Doctor Life product, and research results do not guarantee individual outcomes.

01Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults—A Pilot Study

Ghada Alsaleh, Mohammad Ali, Amir Hossein Kayvanjoo et al.

Aging Cell (2026), 25(6), e70545. DOI: 10.1111/acel.70545; PMID: 42169618.

In a double-blind, randomized pilot study, 40 adults over 65 took 6 mg of spermidine daily for 13 weeks. Supplementation was well tolerated. Participants with weaker vaccine responses showed favorable changes in markers of immune cell aging, autophagy, and selected immune response measures. The study examined spermidine-rich wheat germ extract, not the finished Doctor Life product, but the spermidine amount matched this formula's daily serving.

Read publication ↗

02Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial

Claudia Schwarz, Gloria S. Benson, Nora Horn et al.

JAMA Network Open (2022), 5(5), e2213875. DOI: 10.1001/jamanetworkopen.2022.13875; PMID: 35616942.

In a 12-month study, 100 older adults received wheat germ extract providing 0.9 mg of spermidine daily, or a placebo. The primary memory outcome did not improve significantly, although exploratory analyses suggested areas for further research. The study is important because evidence for cognitive benefits remains inconclusive, and both the dose and purpose of supplementation matter when interpreting results.

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03Supplementation of spermidine at 40 mg/day has minimal effects on circulating polyamines: An exploratory double-blind randomized controlled trial in older men

Patrick Keohane, Jeremy R. Everett, Rui Pereira, Chad M. Cook, Traci M. Blonquist, Eunice Mah

Nutrition Research (2024), 132, 1–14. DOI: 10.1016/j.nutres.2024.09.012; PMID: 39405978.

An exploratory study in older men examined 40 mg of high-purity spermidine daily for 28 days. This amount was well tolerated, but circulating polyamine levels changed little. The publication primarily provides tolerability data for higher doses and shows that blood spermidine levels do not simply mirror oral intake.

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04Spermidine in health and disease

Frank Madeo, Tobias Eisenberg, Federico Pietrocola, Guido Kroemer

Science (2018), 359(6374), eaan2788. DOI: 10.1126/science.aan2788; PMID: 29371440.

This review in Science summarized mechanistic and translational research on spermidine, with particular attention to autophagy and cellular aging. It explains why this natural polyamine has become an important topic in healthy aging research. It provides a biological rationale for the formula's direction, not evidence of a guaranteed clinical benefit from the supplement.

Read publication ↗

FAQ / Spermidine®

Good questions. Clear answers.

Talk to us ↗

What is spermidine, and why is it discussed in longevity research?

Spermidine is a natural polyamine found in the body and many foods. Research interest centers on autophagy, cellular balance, and aging-related biology. It is not a youth hormone or an anti-aging drug, and human evidence is still developing.

Has 6 mg of spermidine been studied in humans?

Yes. A randomized pilot study published in 2026 gave adults over 65 a daily 6 mg serving for 13 weeks. It was well tolerated, and some participants showed changes in immune and autophagy-related markers. The study used the same daily spermidine amount, but did not test the finished Doctor Life product.

Does spermidine “activate autophagy”?

Autophagy is a natural cellular recycling process. Cell and mechanistic studies link spermidine with this process, and a recent trial in older adults reported changes in autophagy-related gene expression in immune cells. These findings do not mean each capsule produces a measurable clinical “cellular detox.”

Is spermidine proven to improve memory?

The evidence is mixed. A small early study suggested potential benefits, but a larger 12-month randomized trial published in 2022, using 0.9 mg daily, did not improve the primary memory measure compared with placebo. Spermidine should not be viewed as a proven memory treatment.

Why use wheat germ concentrate rather than synthetic spermidine?

Wheat germ is a naturally rich source of polyamines. The concentrate provides a stated 6 mg of spermidine per serving. We do not claim that a plant source is clinically superior to a synthetic one; this choice provides a natural source with a clearly specified amount.

Is 6 mg a high amount, and is it safe?

No NRV has been established for spermidine. A 2026 study found 6 mg daily for 13 weeks was well tolerated in older adults. A separate short-term study tested 40 mg daily for 28 days without significant tolerability concerns. These results do not establish safety for every person or long-term use. Follow the product’s recommended serving.

It comes from wheat germ—is it gluten-free?

The finished product is labeled gluten-free, despite its wheat-derived source. People with a wheat allergy should still note that the spermidine comes from wheat germ; gluten-free labeling does not mean wheat-free.

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